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Common Fioricet Interactions

FioricetĀ is a prescription drug that includes the barbiturate butalbital, the pain reliever acetaminophen and caffeine. Some other brand names of this formulation include Capacet, Vanatol and Zebutal.

Fioricet is FDA-approved to treat tension headaches and is prescribed off-label to treat migraines. Fioricet, like all barbiturates, is associated with a high risk of developing dependence and addiction. Even a few Fioricet pills can cause overdose symptoms, and Fioricet overdose is a medical emergency. If you suspect an overdose, call 911 immediately.

Common Fioricet Interactions

  • Alcohol: Mixing Fioricet with alcohol can make you more drowsy and uncoordinated and put extra pressure on your liver.
  • Other Relaxants: Using Fioricet with drugs that slow down the brain, like some painkillers, anxiety meds, or sleep aids, can make you extra sleepy and slow your breathing.
  • MAO Inhibitors: Certain antidepressants can dangerously interact with Fioricet, leading to serious symptoms like confusion, fast heartbeat, and muscle stiffness.
  • Caffeine: Since Fioricet already has caffeine, adding more from coffee or energy drinks can make you feel jittery or restless.
  • Blood Thinners: Fioricet can affect how blood thinners work, increasing the chance of bleeding. Always tell your doctor if you’re on these medications.
  • Liver Medications: Because your liver processes Fioricet, other drugs that affect liver function can impact how Fioricet works, sometimes harming the liver.
  • Stomach Medications: Some drugs for stomach issues can change how your body absorbs Fioricet, affecting its effectiveness.

If you’re using Fioricet and have concerns about how it might interact with other medications or substances, it’s important to talk with your doctor. They can guide you on how to use Fioricet safely, ensuring it helps without causing unwanted problems.

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